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Feeling the heat? Don't sweat it! Check out these evidence-backed strategies to keep your cool.

  • Dr. K Derezil MD
  • Jan 15, 2024
  • 6 min read

If you've reached or approached menopause, you're likely no stranger to hot flashes and night sweats. Though an expected part of the transition, these sudden sensations of intense warmth spreading through the body can range from mildly uncomfortable to severely disruptive for sleep and daily life.


As a professor who researches women's health and aging, I often hear from midlife patients exasperated by frequent, severe vasomotor symptoms (the clinical term for hot flashes and night sweats). The good news is that while not wholly preventable, emerging research shows we can substantially ease the severity and frequency of hot flashes and night sweats with evidence-backed lifestyle and mind-body techniques.


In this blog post, we’ll unpack the latest science on what triggers hot flashes and night sweats, physiological changes contributing to them, and research-supported strategies shown to help manage these unwelcome guests during menopause.


What Triggers Hot Flashes? The Complex Role of Shifting Hormones


During perimenopause and postmenopause, declining estrogen sends confusing signals to the hypothalamus: the brain’s internal thermostat regulating body temperature. Stress and other factors compounding thermostat malfunction worsen hot flashes.


Here’s a closer look at factors influencing their severity and frequency:


  • Declining Estrogen: As the ovaries gradually halt estrogen production over 2-8 years leading up to menopause, circulating estrogen levels fluctuate wildly before declining permanently. These shifting systemic levels confuse the hypothalamus’ temperature regulatory center. Hot flash severity and frequency varies woman-to-woman based partly on how rapidly her estrogen levels change during the menopausal transition.


  • Dysregulated Serotonin: Remember serotonin - the “feel good” neurotransmitter boosting mood and emotional well-being? Researchers are now examining its role in disrupting temperature regulation. Preliminary studies show peri- and postmenopausal women have lower serotonin levels correlated with worse hot flashes. Scientists suspect wonky serotonin signaling confuses the hypothalamus’ thermostat center similarly to fluctuating estrogen.


  • Stress & Anxiety: It likely comes as no surprise that stress, anxiety, and other emotions seem to trigger hot flashes. A recent study monitoring women’s hot flashes and stress levels in real time found worrying, frustration, anxiety, and feeling overwhelmed or impatient often preceded flashes. Brain imaging confirms regions managing stress and emotion processing closely communicate with the hypothalamus’ temperature regulation center.


  • Night Sweats: What about night sweats: episodes of extreme sweating soaking your sleep environment? Turns out night sweats have a slightly different mechanism triggered by diminishing progesterone. Progesterone relaxes vascular smooth muscle tissue. As it declines during the menopausal transition, blood vessels constrict. Constricted peripheral blood vessels inhibit cooling mechanisms activated during sleep, which can wake women up sweat-drenched when their temperature slightly increases.


Lifestyle & Mind-Body Interventions Shown To Lessen Hot Flashes


Now that we better understand the physiological and emotional factors triggering hot flashes and night sweats, let’s explore evidence-based lifestyle changes and mind-body techniques research confirms can meaningfully improve them:


  1. Acupuncture: Acupuncture remains one of the most studied alternative modalities used for menopausal symptoms. This ancient Chinese medicine technique inserts ultra-thin needles into specific body points to modulate energy flow and stimulate healing. Meta-analyses of numerous studies involving thousands of women confirm acupuncture significantly reduces hot flash frequency and severity from peri- through postmenopause. While scientists don’t fully understand the mechanisms, they hypothesize acupuncture regulates heat/stress pathways between muscles, the spinal cord, and parts of the brain influencing body temperature.

  2. Cognitive Behavioral Therapy (CBT): As previously noted, stress and difficult emotions commonly trigger or worsen hot flashes. Cognitive behavioral therapy - focused on identifying, challenging, and neutralizing distressing thought patterns - proves uniquely helpful for managing menopause-related symptoms. Randomized trials find CBT lessens the frequency of self-reported hot flashes. Why? Learning constructive ways of processing emotions and stimuli reducing feelings of stress, irritation, sadness, or anxiety provides tangible symptom relief.

  3. Clinical Hypnosis: Clinical hypnosis guides patients into a deeply relaxed, trance-like state focusing awareness to help reach subconscious parts of the mind. Small randomized trials report hypnosis and self-hypnosis significantly improve hot flashes and sleep quality for some women. Larger studies are needed, but researchers again theorize it works by regulating connections between brain regions controlling temperature, emotions, and perceptions of heat intensity.

  4. Cognitive Mindfulness Meditation: You’ve likely heard about mindfulness meditation’s expansive health and wellness benefits. Applying mindfulness techniques helps calm the mind-body system by intentionally directing non-judgmental awareness to present sensations, thoughts, and emotions. Researchers hypothesize this counteracts stress reactivity worsening hot flashes. Though few quality studies exist yet, early findings report cognitive mindfulness-based interventions (CMBI) meaningfully reduce hot flash frequency and intensity. Controlled trials are ongoing to confirm effects.

  5. Cooling Techniques: Both anecdotally and affirmed through limited clinical research, using external cooling techniques right when a hot flash starts effectively lessens severity. Easy self-care strategies include applying cold washcloths to the face, neck and chest, misting the skin with cooling spray, placing ice packs across pulse points, and sipping cold water. Why it works - direct external cooling apparently overrides confusing temperature signals inside the brain’s thermostat center.

  6. Exercise & Weight Loss for Night Sweats: For disruptive night sweats, regular exercise and maintaining a healthy BMI prove helpful. Increased physical activity supports more restful sleep while assisting healthy vascular function improving temperature regulation. Supporting healthy blood vessel tone may also prevent periphery blood vessel constriction contributing to night sweats. Even moderately increasing fitness levels and shedding excess weight eases night sweat severity for many women.

  7. Herbal Remedies: Herbal and botanical supplements like black cohosh, red clover, and soy/red clover derivatives show modest benefit lessening hot flash frequency and intensity in some studies. However, the American College of Obstetrics and Gynecology still considers evidence supporting their use weak and preliminary due to problematic study designs. Well-controlled future trials may uncover certain botanical supplements providing additional symptom relief. But for now, consulting your doctor before trying supplements remains wise.

  8. Hormone Therapy (HT): Let’s address the elephant in the room - systemic hormone therapy (HT), containing formulations of estrogen with or without progesterone. Oral HT used to be routinely prescribed to treat hot flashes and night sweats until the Women’s Health Initiative revealed health risks like stroke and breast cancer associated long-term use. However, transdermal HT delivery through skin patches and gels proves much safer with lower risks. Today, short term HT is once again considered the most efficacious treatment for moderate to severe vasomotor symptoms negatively impacting quality of life. Of course, discussing HT’s pros and cons with your clinician remains imperative before starting.


Putting It All Together: An Integrative Approach for Managing Hot Flashes & Night Sweats


Rather than any single solution, an integrative approach combining several evidence-based techniques offers the best results tailoring relief to each woman’s symptoms and needs.

I advise my patients to start with safer lifestyle measures like acupuncture, mindfulness meditation, cooling techniques, exercise, stress and sleep hygiene. Integrating cognitive behavioral therapy addresses unhelpful thought patterns and emotional reactivity worsening symptoms. For disruptive night sweats, maintaining a healthy weight through nutrition and activity can ease severity.



I reserve hormone therapy only for women with moderate to severe daily symptoms negatively impacting work, relationships and rest after reviewing health history for contraindications. When quality of life suffers, short term hormone therapy helps bridge the gap until natural menopause progression and lifespan reduce symptom frequency and intensity.


Some women need extra support beyond lifestyle measures if symptoms don’t improve in 6-8 weeks. Based on each patient’s medical profile and availability in their region, I may suggest one or more of the following: clinical hypnosis, herbal supplements, low-dose antidepressants, gabapentin, clonidine, SSRIs, or SNRIs. All these conventional and complementary medical therapies demonstrate modest but measurable effects lessening hot flash frequency, severity and night sweats.


The key is tailoring evidence-based therapies to each woman’s symptoms, health history and ability to access treatment. While no magic bullet exists yet, the good news is continuing research and emerging options provide more paths bringing relief through the menopausal tunnel.


If you’re struggling with particularly bothersome hot flashes or night sweats, I encourage you to consult a trusted clinician. Discuss all treatment considerations and create an integrative plan aligning your preferences, symptoms and medical needs. With a proactive approach tapping available resources, you can minimize the daily burden of disruptive vasomotor symptoms and sleep better during the menopausal transition and beyond.


I wish you resilient health,


Professor Peri


"I am equipped to handle whatever arises on my menopausal journey with wisdom, grace and compassion for myself and others."

 
 
 

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